The Antidote: Inside the World of New Pharma

Cover The Antidote: Inside the World of New Pharma
Bush was inaugurated in a bone-chilling drizzle, the FDA approved Schering-Plough’s Pegintron for the treatment of patients with chronic hepatitis C. The drug was the first once-weekly injection of genetically engineered alpha interferon, a biological molecule released to help uninfected host cells resist new infection by a virus. In a study of more than a thousand patients comparing Pegintron to the company’s decade-old Intron A, which was shorter acting and taken three times a week, it double...d the cure rate to 24 percent when taken for forty-eight weeks. More than half the patients in the study complained of flu-like reactions: fevers, chills, muscle aches, sweating, exhaustion. A third of them reported being depressed. Roche, too, had filed for approval for a longer-acting interferon, Pegasys, setting up a marketing war as both companies began further studies combining the new medicines with a second broad-spectrum antiviral, ribavirin.
In the collaboration with Lilly, Vertex rediscovered that HCV wouldn’t yield to the usual stratagems.
MoreLess

Read book The Antidote: Inside the World of New Pharma for free

You can download books for free in various formats, such as epub, pdf, azw, mobi, txt and others on book networks site. Additionally, the entire text is available for online reading through our e-reader. Our site is not responsible for the performance of third-party products (sites).
Ads Skip 5 sec Skip
+Write review

User Reviews:

Write Review:

Guest

Guest