Frameshift
“said Molly, sitting on a stool in Pierre’s lab. It was ten o’clock on a Saturday morning. “I want to understand exactly what’s happening.”
Pierre nodded. “Okay,” he said. “On Thursday, I extracted samples of my DNA from a drop of my own blood. I separated out my two copies of chromosome four, snipped off particular segments using special enzymes, and set about making radioactive images of those segments. It takes a while to develop those images, but they should be ready now, so we can actua...lly check what my genetic code says in the specific gene associated with Huntington’s disease. That gene contains an area called IT15 — ‘interesting transcript number fifteen,’ a name given to it back when people didn’t know what it was for.”
“And if you’ve got IT15, you’ve got Huntington’s?”
“It’s not as simple as that. Everybody has IT15. Like all genes, IT15’s job is to code for the synthesis of a protein molecule.MoreLess
Pierre nodded. “Okay,” he said. “On Thursday, I extracted samples of my DNA from a drop of my own blood. I separated out my two copies of chromosome four, snipped off particular segments using special enzymes, and set about making radioactive images of those segments. It takes a while to develop those images, but they should be ready now, so we can actua...lly check what my genetic code says in the specific gene associated with Huntington’s disease. That gene contains an area called IT15 — ‘interesting transcript number fifteen,’ a name given to it back when people didn’t know what it was for.”
“And if you’ve got IT15, you’ve got Huntington’s?”
“It’s not as simple as that. Everybody has IT15. Like all genes, IT15’s job is to code for the synthesis of a protein molecule.MoreLess
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