Avoid Boring People: Lessons From a Life in Science
“MANNERS PASSED ON TO AN ASPIRING YOUNG SCIENTISTUPON my return to the less intense intellectual atmosphere of IU in the fall of 1948, I began following up Luria's observations from 1941 that phages suspended in simple salt solutions are much more sensitive to inactivation by X-rays than those suspended in nutrient-rich beef broth solutions. Unclear was whether phages indirectly killed by exposure to reactive molecules generated by X-rays striking surrounding water molecules possessed novel prop...erties not found in phages killed by “direct” X-ray hits. Luria's earlier inactivation curves suggested that several indirect hits were required to kill a phage. In contrast, direct killing was long thought to result from a single ionization event.While enjoying the first experiments of my own devising, I began anticipating the intellectual excitement that was to come from the impending mid-October weekend visit of Leo Szilard. Just turned fifty, Szilard was then a professor of biophysics and sociology at the University of Chicago, and was driven down by his much younger collaborator, Aaron Novick, also a participant in the 1947 Cold Spring Harbor phage course.MoreLess
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