“Specimen Number:JL01-99438 Hematology Associates Emory University Hospital, Suite 2010 Atlanta, GA 30020 Date Collected: 4/04 Date Received: 4/04 Date Reported: 4/05 Diagnosis: Acute Lymphoblastic Leukemia Gross Description The specimen consists of 6 slides and 3 additional aliquots of 3 cc each, labeled “Bone Marrow Aspirate, Melinda Skye.” Microscopic Description: The bone marrow aspirate demonstrates extensive hypercellularity with normal bone marrow elements essentially replaced by infi...ltrating lymphoblasts. There are multiple mitotic figures seen. The lymphoblasts demonstrate a high nuclear/cytoplasm ratio and clumped nuclear chromatin. Some nuclei display a folded appearance. Scattered among the abnormal cells are small numbers of erythroid, myeloid, and megakaryocytic cells. Flow cytometric immunophenotypic studies demonstrated a population of beta lymphocytes, which expressed the CD19 and CD20 antigens. Cytochemistry was positive for TdT, further corroborating a lymphoblastic process.MoreLessRead More Read Less
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